Laura Bagnale is a PhD student at University of Campania “L. Vanvitelli”. Her research in the past three years focused on studies for the construction of a Boron Neutron Capture Therapy (BNCT) facility that will be built in Caserta, Italy. The first part of her studies were dedicated to use the Monte Carlo for N-particle (MCNP) simulation code to reproduce the structure of the facility. This part of her work was devoted to simulate the interaction of the neutron beam with the facility materials with the aim to optimize the layout in terms of geometry and compositions, to ensure the structure from the radiation protection point of view to guaratee the safety of the staff, patiens and citizens. She also collaborated to the design of the Beam Shaping Assembly, a key structure to tailor the most effective and safe clinical neutron beam. Another part of her work was to study the BNCT radiobiological effect on tumoral and healthy cells. To reach this objective she joint cell colture irradiation experiments at the laboratory of the University (CIRCE-LAB), which is equipped with a tandem particle accelerator, and she used Geant4-DNA tool to simulate the BNCT mixed field interaction with cells. By modifying the original input file of the “moleculardna” (advanced example of Geant4-DNA), she had the opportunity to model detailed simulations and study the connection between DNA damages and boron micro biodistribution of Boron-10 inside the cell environment, by enanching the data and knowledge in the BNCT.